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PRMT5 Promotes Cyclin E1 and Cell Cycle Progression in CD4 Th1 Cells and Correlates With EAE Severity

Multiple Sclerosis (MS) is a debilitating central nervous system disorder associated with inflammatory T cells. Activation and expansion of inflammatory T cells is thought to be behind MS relapses and influence disease severity. Protein arginine N-methyltransferase 5 (PRMT5) is a T cell activation-i...

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Detalles Bibliográficos
Autores principales: Amici, Stephanie A., Osman, Wissam, Guerau-de-Arellano, Mireia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217861/
https://www.ncbi.nlm.nih.gov/pubmed/34168658
http://dx.doi.org/10.3389/fimmu.2021.695947