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Optimal control for colistin dosage selection

Optimization of antibiotic administration helps minimizing cases of bacterial resistance. Dosages are often selected by trial and error using a pharmacokinetic (PK) model. However, this is limited to the range of tested dosages, restraining possible treatment choices, especially for the loading dose...

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Detalles Bibliográficos
Autores principales: Gontijo, Aline Vidal Lacerda, Cavalieri, André V. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217983/
https://www.ncbi.nlm.nih.gov/pubmed/34156631
http://dx.doi.org/10.1007/s10928-021-09769-6