TDP-43 Mutation Affects Stress Granule Dynamics in Differentiated NSC-34 Motoneuron-Like Cells

Amyotrophic Lateral Sclerosis (ALS) is characterized by degeneration of motor neurons in the brain and spinal cord. Cytoplasmic inclusions of TDP-43 are frequently reported in motor neurons of ALS patients. TDP-43 has also been shown to associate with stress granules (SGs), a complex of proteins and...

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Detalles Bibliográficos
Autores principales: Ding, Qiao, Chaplin, Justin, Morris, Matthew J., Hilliard, Massimo A., Wolvetang, Ernst, Ng, Dominic C. H., Noakes, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217991/
https://www.ncbi.nlm.nih.gov/pubmed/34169068
http://dx.doi.org/10.3389/fcell.2021.611601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217991/
https://www.ncbi.nlm.nih.gov/pubmed/34169068
http://dx.doi.org/10.3389/fcell.2021.611601

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