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Three-dimensional cultured mesenchymal stem cells enhance repair of ischemic stroke through inhibition of microglia

BACKGROUND: We show previously that three-dimensional (3D) spheroid cultured mesenchymal stem cells (MSCs) exhibit reduced cell size thus devoid of lung entrapment following intravenous (IV) infusion. In this study, we determined the therapeutic effect of 3D-cultured MSCs on ischemic stroke and inve...

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Detalles Bibliográficos
Autores principales: Li, Yuejiao, Dong, Yankai, Ran, Ye, Zhang, Yanan, Wu, Boyao, Xie, Jundong, Cao, Yanpei, Mo, Miaohua, Li, Sen, Deng, Hao, Hao, Wenbo, Yu, Shengyuan, Wu, Yaojiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218508/
https://www.ncbi.nlm.nih.gov/pubmed/34154653
http://dx.doi.org/10.1186/s13287-021-02416-4