Synthesis of 1-indolyl-3,5,8-substituted γ-carbolines: one-pot solvent-free protocol and biological evaluation

1,5-Disubstituted indole-2-carboxaldehyde derivatives 1a–h and glycine alkyl esters 2a–c are shown to undergo a novel cascade imination-heterocylization in the presence of the organic base DIPEA to provide 1-indolyl-3,5,8-substituted γ-carbolines 3aa–ea in good yields. The γ-carbolines are fluoresce...

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Detalles Bibliográficos
Autores principales: Dudhe, Premansh, Krishnan, Mena Asha, Yadav, Kratika, Roy, Diptendu, Venkatasubbaiah, Krishnan, Pathak, Biswarup, Chelvam, Venkatesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218543/
https://www.ncbi.nlm.nih.gov/pubmed/34221174
http://dx.doi.org/10.3762/bjoc.17.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218543/
https://www.ncbi.nlm.nih.gov/pubmed/34221174
http://dx.doi.org/10.3762/bjoc.17.101

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