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Development of a Broth Microdilution Method for Exebacase Susceptibility Testing

Exebacase (CF-301) belongs to a new class of protein-based antibacterial agents, known as lysins (peptidoglycan hydrolases). Exebacase, a novel lysin with antistaphylococcal activity, is in phase 3 of clinical development. To advance into the clinic, it was necessary to develop an accurate and repro...

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Detalles Bibliográficos
Autores principales: Oh, Jun T., Ambler, Jane E., Cassino, Cara, Schuch, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218677/
https://www.ncbi.nlm.nih.gov/pubmed/33903102
http://dx.doi.org/10.1128/AAC.02587-20