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Increased frequency of TIGIT(+)CD73-CD8(+) T cells with a TOX(+) TCF-1low profile in patients with newly diagnosed and relapsed AML

The inhibitory receptor TIGIT, as well as theectonucleotidases CD39 and CD73 constitute potential exhaustion markers for T cells. Detailed analysis of these markers can shed light into dysregulation of the T-cell response in acute myeloid leukemia (AML) and will help to identify potential therapeuti...

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Detalles Bibliográficos
Autores principales: Brauneck, F., Haag, F, Woost, R., Wildner, N., Tolosa, E., Rissiek, A., Vohwinkel, G., Wellbrock, J., Bokemeyer, C., Schulze zur Wiesch, J., Ackermann, C., Fiedler, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218695/
https://www.ncbi.nlm.nih.gov/pubmed/34211801
http://dx.doi.org/10.1080/2162402X.2021.1930391