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A pharmacokinetics–pharmacodynamics study of single-dose total glucosides of paeony capsule on reducing serum total bile acid in hepatic injury rats

CONTEXT: Total Glucosides of Paeony (TGP) capsule possesses various hepatoprotective activities. No study is available concerning TGP’s concentration–effect relationship on hepatoprotection. OBJECTIVE: To establish a pharmacokinetics–pharmacodynamics (PK-PD) modelling on TGP capsule’s hepatoprotecti...

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Detalles Bibliográficos
Autores principales: Jiang, Ninghua, Zheng, Bohong, Feng, Yihan, Yin, Lei, Liu, Yuanrong, Cao, Lujing, Zheng, Ning, Wu, Suxiang, Ding, Baoyue, Huang, Xuan, Wang, Jeffrey, Zhan, Shuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218697/
https://www.ncbi.nlm.nih.gov/pubmed/34152236
http://dx.doi.org/10.1080/13880209.2021.1937232