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Quantitative Real-Time PCR Assays for the Detection of Pathogenic Leptospira Species in Urine and Blood Samples in Canine Vaccine Clinical Studies: a Rapid Alternative to Classical Culture Methods

Leptospirosis is a vaccine-preventable bacterial zoonotic disease caused by pathogenic Leptospira species. The efficacy of Leptospira canine vaccines is assessed by challenging vaccinated and control dogs with virulent serovars of Leptospira, followed by detection of Leptospira in blood and urine. W...

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Detalles Bibliográficos
Autores principales: Blanchard, Stephanie, Cariou, Carine, Bouvet, Jérôme, Valfort, William, Oberli, Frantz, Villard, Séverine, Barret-Hilaire, Florence, Poulet, Hervé, Cupillard, Lionel, de Saint-Vis, Blandine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218769/
https://www.ncbi.nlm.nih.gov/pubmed/33853840
http://dx.doi.org/10.1128/JCM.03006-20