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Investigating Tumor Heterogeneity in Mouse Models
Cancer arises from a single cell through a series of acquired mutations and epigenetic alterations. Tumors gradually develop into a complex tissue comprised of phenotypically heterogeneous cancer cell populations, as well as noncancer cells that make up the tumor microenvironment. The phenotype, or...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218894/ https://www.ncbi.nlm.nih.gov/pubmed/34164589 http://dx.doi.org/10.1146/annurev-cancerbio-030419-033413 |