A computational method for direct imputation of cell type-specific expression profiles and cellular compositions from bulk-tissue RNA-Seq in brain disorders

The importance of cell type-specific gene expression in disease-relevant tissues is increasingly recognized in genetic studies of complex diseases. However, most gene expression studies are conducted on bulk tissues, without examining cell type-specific expression profiles. Several computational met...

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Detalles Bibliográficos
Autores principales: Doostparast Torshizi, Abolfazl, Duan, Jubao, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219045/
https://www.ncbi.nlm.nih.gov/pubmed/34169279
http://dx.doi.org/10.1093/nargab/lqab056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219045/
https://www.ncbi.nlm.nih.gov/pubmed/34169279
http://dx.doi.org/10.1093/nargab/lqab056

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