Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice

Dengue virus (DENV), a Flavivirus, causes a broad spectrum of disease in humans with key clinical signs including thrombocytopenia, vascular leakage and hemorrhaging. A major obstacle to understanding DENV immunity has been the lack of a validated immune-competent mouse model. Here, we report the in...

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Detalles Bibliográficos
Autores principales: Rathore, Abhay P. S., Mantri, Chinmay K., Tan, Meredith W., Shirazi, Roksana, Nishida, Andrew, Aman, Siti A. B., Morrison, Juliet, St. John, Ashley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219075/
https://www.ncbi.nlm.nih.gov/pubmed/34168651
http://dx.doi.org/10.3389/fimmu.2021.681950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219075/
https://www.ncbi.nlm.nih.gov/pubmed/34168651
http://dx.doi.org/10.3389/fimmu.2021.681950

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