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Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice
Dengue virus (DENV), a Flavivirus, causes a broad spectrum of disease in humans with key clinical signs including thrombocytopenia, vascular leakage and hemorrhaging. A major obstacle to understanding DENV immunity has been the lack of a validated immune-competent mouse model. Here, we report the in...
Autores principales: | Rathore, Abhay P. S., Mantri, Chinmay K., Tan, Meredith W., Shirazi, Roksana, Nishida, Andrew, Aman, Siti A. B., Morrison, Juliet, St. John, Ashley L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219075/ https://www.ncbi.nlm.nih.gov/pubmed/34168651 http://dx.doi.org/10.3389/fimmu.2021.681950 |
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