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Proinflammatory responses in SARS-CoV-2 infected and soluble spike glycoprotein S1 subunit activated human macrophages

Critically ill COVID-19 patients infected with SARS-CoV-2 display signs of generalized hyperinflammation. Macrophages trigger inflammation to eliminate pathogens and repair tissue, but this process can also lead to hyperinflammation and resulting exaggerated disease. The role of macrophages in dysre...

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Detalles Bibliográficos
Autores principales: Chiok, Kim, Hutchison, Kevin, Miller, Lindsay Grace, Bose, Santanu, Miura, Tanya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219098/
https://www.ncbi.nlm.nih.gov/pubmed/34159334
http://dx.doi.org/10.1101/2021.06.14.448426