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Proinflammatory responses in SARS-CoV-2 infected and soluble spike glycoprotein S1 subunit activated human macrophages
Critically ill COVID-19 patients infected with SARS-CoV-2 display signs of generalized hyperinflammation. Macrophages trigger inflammation to eliminate pathogens and repair tissue, but this process can also lead to hyperinflammation and resulting exaggerated disease. The role of macrophages in dysre...
Autores principales: | Chiok, Kim, Hutchison, Kevin, Miller, Lindsay Grace, Bose, Santanu, Miura, Tanya A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219098/ https://www.ncbi.nlm.nih.gov/pubmed/34159334 http://dx.doi.org/10.1101/2021.06.14.448426 |
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