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Structures of synthetic nanobody–SARS-CoV-2–RBD complexes reveal distinct sites of interaction and recognition of variants

The worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and emergence of new variants demands understanding the structural basis of the interaction of antibodies with the SARS-CoV-2 receptor-binding domain (RBD). Here we report five X-ray crystal structures of sybodies (...

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Detalles Bibliográficos
Autores principales: Ahmad, Javeed, Jiang, Jiansheng, Boyd, Lisa F., Zeher, Allison, Huang, Rick, Xia, Di, Natarajan, Kannan, Margulies, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219104/
https://www.ncbi.nlm.nih.gov/pubmed/34159326
http://dx.doi.org/10.21203/rs.3.rs-625642/v1