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Long non-coding RNA KIKAT/LINC01061 as a novel epigenetic regulator that relocates KDM4A on chromatin and modulates viral reactivation

KDM4A is a histone lysine demethylase that has been described as an oncogene in various types of cancer. The importance of KDM4A-mediated epigenetic regulation in tumorigenesis is just emerging. Here, by using Kaposi’s sarcoma associated herpesvirus (KSHV) as a screening model, we identified 6 oncog...

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Detalles Bibliográficos
Autores principales: Yang, Wan-Shan, Yeh, Wayne W., Campbell, Mel, Chang, Lung, Chang, Pei-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219169/
https://www.ncbi.nlm.nih.gov/pubmed/34111227
http://dx.doi.org/10.1371/journal.ppat.1009670