Blocking the CCL5–CCR5 Axis Using Maraviroc Promotes M1 Polarization of Macrophages Cocultured with Irradiated Hepatoma Cells

PURPOSE: The C-C chemokine ligand 5 (CCL5)–C-C chemokine receptor (CCR5) axis facilitates tumor progression via multiple mechanisms. Herein, we elucidated the effect of a CCR5 antagonist (maraviroc [MVC]; blocking the CCL5–CCR5 axis) on the phenotype of macrophages cocultured with irradiated hepatom...

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Detalles Bibliográficos
Autores principales: Zhuang, Yuan, Zhao, Xiaomei, Yuan, Baoying, Zeng, Zhaochong, Chen, Yixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219307/
https://www.ncbi.nlm.nih.gov/pubmed/34178876
http://dx.doi.org/10.2147/JHC.S300165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219307/
https://www.ncbi.nlm.nih.gov/pubmed/34178876
http://dx.doi.org/10.2147/JHC.S300165

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