Cargando…

A putative structural mechanism underlying the antithetic effect of homologous RND1 and RhoD GTPases in mammalian plexin regulation

Plexins are semaphorin receptors that play essential roles in mammalian neuronal axon guidance and in many other important mammalian biological processes. Plexin signaling depends on a semaphorin-induced dimerization mechanism and is modulated by small GTPases of the Rho family, of which RND1 serves...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yanyan, Ke, Pu, Kuo, Yi-Chun, Wang, Yuxiao, Zhang, Xuewu, Song, Chen, Shan, Yibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219378/
https://www.ncbi.nlm.nih.gov/pubmed/34114565
http://dx.doi.org/10.7554/eLife.64304