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Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells

BACKGROUND: Marrow adipose tissue (MAT) has been shown to be vital for regulating metabolism and maintaining skeletal homeostasis in the bone marrow (BM) niche. As a reflection of BM remodeling, MAT is highly responsive to nutrient fluctuations, hormonal changes, and metabolic disturbances such as o...

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Detalles Bibliográficos
Autores principales: Aaron, Nicole, Kraakman, Michael J, Zhou, Qiuzhong, Liu, Qiongming, Costa, Samantha, Yang, Jing, Liu, Longhua, Yu, Lexiang, Wang, Liheng, He, Ying, Fan, Lihong, Hirakawa, Hiroyuki, Ding, Lei, Lo, James, Wang, Weidong, Zhao, Baohong, Guo, Edward, Sun, Lei, Rosen, Cliff J, Qiang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219379/
https://www.ncbi.nlm.nih.gov/pubmed/34155972
http://dx.doi.org/10.7554/eLife.69209