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The discriminatory power of the T cell receptor

T cells use their T cell receptors (TCRs) to discriminate between lower-affinity self and higher-affinity non-self peptides presented on major histocompatibility complex (pMHC) antigens. Although the discriminatory power of the TCR is widely believed to be near-perfect, technical difficulties have h...

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Detalles Bibliográficos
Autores principales: Pettmann, Johannes, Huhn, Anna, Abu Shah, Enas, Kutuzov, Mikhail A, Wilson, Daniel B, Dustin, Michael L, Davis, Simon J, van der Merwe, P Anton, Dushek, Omer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219380/
https://www.ncbi.nlm.nih.gov/pubmed/34030769
http://dx.doi.org/10.7554/eLife.67092