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Locating macromolecular assemblies in cells by 2D template matching with cisTEM

For a more complete understanding of molecular mechanisms, it is important to study macromolecules and their assemblies in the broader context of the cell. This context can be visualized at nanometer resolution in three dimensions (3D) using electron cryo-tomography, which requires tilt series to be...

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Detalles Bibliográficos
Autores principales: Lucas, Bronwyn A, Himes, Benjamin A, Xue, Liang, Grant, Timothy, Mahamid, Julia, Grigorieff, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219381/
https://www.ncbi.nlm.nih.gov/pubmed/34114559
http://dx.doi.org/10.7554/eLife.68946