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Serum Exosomes Derived from Irritable Bowel Syndrome Patient Increase Cell Permeability via Regulating miR-148b-5p/RGS2 Signaling in Human Colonic Epithelium Cells

AIM: Irritable bowel syndrome (IBS) is a multifactorial functional bowel disorder characterized by disruption of the intestinal barrier. Circulating exosomal microRNAs (miRNAs) are involved in regulating epithelial barrier function, and upregulation of miR-148b-5p has been detected in IBS. However,...

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Detalles Bibliográficos
Autores principales: Xing, Ying, Xue, Shan, Wu, Jing, Zhou, Jianhong, Xing, Fangfang, Li, Tianxing, Nie, Xiaohu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219443/
https://www.ncbi.nlm.nih.gov/pubmed/34221007
http://dx.doi.org/10.1155/2021/6655900