Transcription factor NF-κB as target for SARS-CoV-2 drug discovery efforts using inflammation-based QSAR screening model

NF-κB is a central regulator of immunity and inflammation. It is suggested that the inflammatory response mediated by SARS-CoV-2 is predominated by NF-κB activation. Thus, NF-κB inhibition is considered a potential therapeutic strategy for COVID-19. The aim of this study was to identify potential an...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanan, Tarek, Kanan, Duaa, Al Shardoub, Ebrahim Jaafar, Durdagi, Serdar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219481/
https://www.ncbi.nlm.nih.gov/pubmed/34311260
http://dx.doi.org/10.1016/j.jmgm.2021.107968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219481/
https://www.ncbi.nlm.nih.gov/pubmed/34311260
http://dx.doi.org/10.1016/j.jmgm.2021.107968

Ejemplares similares