NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexpressing Mice

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) is a central regulator of cellular stress responses and its transcriptional activation promotes multiple cellular defense and survival mechanisms. The loss of NRF2 has been shown to increase oxidative and proteotoxic stress, two key pathological fea...

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Detalles Bibliográficos
Autores principales: Anandhan, Annadurai, Nguyen, Nhat, Syal, Arjun, Dreher, Luke A, Dodson, Matthew, Zhang, Donna D, Madhavan, Lalitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219498/
https://www.ncbi.nlm.nih.gov/pubmed/34221542
http://dx.doi.org/10.14336/AD.2021.0511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219498/
https://www.ncbi.nlm.nih.gov/pubmed/34221542
http://dx.doi.org/10.14336/AD.2021.0511

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