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Functional evidence of distinct electrophile-induced activation states of the ion channel TRPA1

Transient Receptor Potential Ankyrin 1 (TRPA1) is a tetrameric, nonselective cation channel expressed on nociceptive sensory nerves whose activation elicits nocifensive responses (e.g. pain). TRPA1 is activated by electrophiles found in foods and pollution, or produced during inflammation and oxidat...

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Detalles Bibliográficos
Autores principales: Parks, Thomas A., Bahia, Parmvir K., Taylor-Clark, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219651/
https://www.ncbi.nlm.nih.gov/pubmed/34189279
http://dx.doi.org/10.1016/j.bbrep.2021.101044