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Functional evidence of distinct electrophile-induced activation states of the ion channel TRPA1
Transient Receptor Potential Ankyrin 1 (TRPA1) is a tetrameric, nonselective cation channel expressed on nociceptive sensory nerves whose activation elicits nocifensive responses (e.g. pain). TRPA1 is activated by electrophiles found in foods and pollution, or produced during inflammation and oxidat...
Autores principales: | Parks, Thomas A., Bahia, Parmvir K., Taylor-Clark, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219651/ https://www.ncbi.nlm.nih.gov/pubmed/34189279 http://dx.doi.org/10.1016/j.bbrep.2021.101044 |
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