Inhibition of MRN activity by a telomere protein motif

The MRN complex (MRX in Saccharomyces cerevisiae, made of Mre11, Rad50 and Nbs1/Xrs2) initiates double-stranded DNA break repair and activates the Tel1/ATM kinase in the DNA damage response. Telomeres counter both outcomes at chromosome ends, partly by keeping MRN-ATM in check. We show that MRX is d...

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Detalles Bibliográficos
Autores principales: Khayat, Freddy, Cannavo, Elda, Alshmery, Majedh, Foster, William R., Chahwan, Charly, Maddalena, Martino, Smith, Christopher, Oliver, Antony W., Watson, Adam T., Carr, Antony M., Cejka, Petr, Bianchi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219681/
https://www.ncbi.nlm.nih.gov/pubmed/34158470
http://dx.doi.org/10.1038/s41467-021-24047-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219681/
https://www.ncbi.nlm.nih.gov/pubmed/34158470
http://dx.doi.org/10.1038/s41467-021-24047-2

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