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Autophagy of mucin granules contributes to resolution of airway mucous metaplasia

Exacerbations of muco-obstructive airway diseases such as COPD and asthma are associated with epithelial changes termed mucous metaplasia (MM). Many molecular pathways triggering MM have been identified; however, the factors that regulate resolution are less well understood. We hypothesized that the...

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Detalles Bibliográficos
Autores principales: Sweeter, J. M., Kudrna, K., Hunt, K., Thomes, P., Dickey, B. F., Brody, S. L., Dickinson, J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219712/
https://www.ncbi.nlm.nih.gov/pubmed/34158522
http://dx.doi.org/10.1038/s41598-021-91932-7