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Targeted SPION siderophore conjugate loaded with doxorubicin as a theranostic agent for imaging and treatment of colon carcinoma

Recently, the siderophores have opened new horizons in nanomedicine. The current study aimed to design a theranostic platform based on superparamagnetic iron oxide nanoparticles-pyoverdine (SPION/PVD) conjugates bound to MUC1 aptamer (MUC1(Apt)) and loaded with doxorubicin (DOX) as an anti-cancer ag...

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Detalles Bibliográficos
Autores principales: Nosrati, Rahim, Abnous, Khalil, Alibolandi, Mona, Mosafer, Jafar, Dehghani, Sadegh, Taghdisi, Seyed Mohammad, Ramezani, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219724/
https://www.ncbi.nlm.nih.gov/pubmed/34158526
http://dx.doi.org/10.1038/s41598-021-92391-w