Intratracheal inoculation of AHc vaccine induces protection against aerosolized botulinum neurotoxin A challenge in mice

Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is generally known to be the most poisonous of all biological toxins. In this study, we evaluate the protection conferred by intratracheal (i.t.) inoculation immunization with recombinant Hc subunit (AHc) vaccines against aerosolized Bo...

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Detalles Bibliográficos
Autores principales: Gan, Changjiao, Luo, Wenbo, Yu, Yunzhou, Jiao, Zhouguang, Li, Sha, Su, Duo, Feng, Junxia, Zhao, Xiaodong, Qiu, Yefeng, Hu, Lingfei, Zhou, Dongsheng, Xiong, Xiaolu, Wang, Jinglin, Yang, Huiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219734/
https://www.ncbi.nlm.nih.gov/pubmed/34158496
http://dx.doi.org/10.1038/s41541-021-00349-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219734/
https://www.ncbi.nlm.nih.gov/pubmed/34158496
http://dx.doi.org/10.1038/s41541-021-00349-w

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