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Intratracheal inoculation of AHc vaccine induces protection against aerosolized botulinum neurotoxin A challenge in mice
Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is generally known to be the most poisonous of all biological toxins. In this study, we evaluate the protection conferred by intratracheal (i.t.) inoculation immunization with recombinant Hc subunit (AHc) vaccines against aerosolized Bo...
Autores principales: | Gan, Changjiao, Luo, Wenbo, Yu, Yunzhou, Jiao, Zhouguang, Li, Sha, Su, Duo, Feng, Junxia, Zhao, Xiaodong, Qiu, Yefeng, Hu, Lingfei, Zhou, Dongsheng, Xiong, Xiaolu, Wang, Jinglin, Yang, Huiying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219734/ https://www.ncbi.nlm.nih.gov/pubmed/34158496 http://dx.doi.org/10.1038/s41541-021-00349-w |
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