Cargando…

Dissecting regulatory pathways for transcription recovery following DNA damage reveals a non-canonical function of the histone chaperone HIRA

Transcription restart after a genotoxic challenge is a fundamental yet poorly understood process. Here, we dissect the interplay between transcription and chromatin restoration after DNA damage by focusing on the human histone chaperone complex HIRA, which is required for transcription recovery post...

Descripción completa

Detalles Bibliográficos
Autores principales: Bouvier, Déborah, Ferrand, Juliette, Chevallier, Odile, Paulsen, Michelle T., Ljungman, Mats, Polo, Sophie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219801/
https://www.ncbi.nlm.nih.gov/pubmed/34158510
http://dx.doi.org/10.1038/s41467-021-24153-1