Anthrax toxin translocation complex reveals insight into the lethal factor unfolding and refolding mechanism

Translocation is essential to the anthrax toxin mechanism. Protective antigen (PA), the binding component of this AB toxin, forms an oligomeric pore that translocates lethal factor (LF) or edema factor, the active components of the toxin, into the cell. Structural details of the translocation proces...

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Detalles Bibliográficos
Autores principales: Machen, Alexandra J., Fisher, Mark T., Freudenthal, Bret D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219829/
https://www.ncbi.nlm.nih.gov/pubmed/34158520
http://dx.doi.org/10.1038/s41598-021-91596-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219829/
https://www.ncbi.nlm.nih.gov/pubmed/34158520
http://dx.doi.org/10.1038/s41598-021-91596-3

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