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Anthrax toxin translocation complex reveals insight into the lethal factor unfolding and refolding mechanism
Translocation is essential to the anthrax toxin mechanism. Protective antigen (PA), the binding component of this AB toxin, forms an oligomeric pore that translocates lethal factor (LF) or edema factor, the active components of the toxin, into the cell. Structural details of the translocation proces...
Autores principales: | Machen, Alexandra J., Fisher, Mark T., Freudenthal, Bret D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219829/ https://www.ncbi.nlm.nih.gov/pubmed/34158520 http://dx.doi.org/10.1038/s41598-021-91596-3 |
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