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Real-time identification of two substrate-binding intermediates for the light-driven sodium pump rhodopsin

Membrane transport proteins undergo critical conformational changes during substrate uptake and release, as the substrate-binding site is believed to switch its accessibility from one side of the membrane to the other. Thus, at least two substrate-binding intermediates should appear during the proce...

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Detalles Bibliográficos
Autores principales: Kato, Tomoya, Tsukamoto, Takashi, Demura, Makoto, Kikukawa, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219890/
https://www.ncbi.nlm.nih.gov/pubmed/34019877
http://dx.doi.org/10.1016/j.jbc.2021.100792