Atorvastatin induces adrenal androgen downshift in men with prostate cancer: A post Hoc analysis of a pilot adaptive Randomised clinical trial

BACKGROUND: Prostate cancer (PCa) progression depends on androgen receptor activity. Cholesterol is required for biosynthesis of all steroid hormones, including androgens. Impact of cholesterol-lowering statins on androgens is unknown. We explored atorvastatin influence on serum and prostatic tissue...

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Detalles Bibliográficos
Autores principales: Raittinen, Paavo V.H., Syvälä, Heimo, Tammela, Teuvo L.J., Häkkinen, Merja R., Ilmonen, Pauliina, Auriola, Seppo, Murtola, Teemu J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219992/
https://www.ncbi.nlm.nih.gov/pubmed/34144486
http://dx.doi.org/10.1016/j.ebiom.2021.103432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219992/
https://www.ncbi.nlm.nih.gov/pubmed/34144486
http://dx.doi.org/10.1016/j.ebiom.2021.103432

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