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Curcumin pre-treatment may protect against mitochondrial damage in LRRK2-mutant Parkinson's disease and healthy control fibroblasts

Mitochondrial dysfunction has been proposed as one of the pathobiological underpinnings in Parkinson's disease. Environmental stressors, such as paraquat, induce mitochondrial dysfunction and promote reactive oxygen species production. Targeting oxidative stress pathways could prevent mitochond...

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Detalles Bibliográficos
Autores principales: Abrahams, Shameemah, Miller, Hayley C., Lombard, Carl, van der Westhuizen, Francois H., Bardien, Soraya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219994/
https://www.ncbi.nlm.nih.gov/pubmed/34189277
http://dx.doi.org/10.1016/j.bbrep.2021.101035