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Curcumin pre-treatment may protect against mitochondrial damage in LRRK2-mutant Parkinson's disease and healthy control fibroblasts
Mitochondrial dysfunction has been proposed as one of the pathobiological underpinnings in Parkinson's disease. Environmental stressors, such as paraquat, induce mitochondrial dysfunction and promote reactive oxygen species production. Targeting oxidative stress pathways could prevent mitochond...
Autores principales: | Abrahams, Shameemah, Miller, Hayley C., Lombard, Carl, van der Westhuizen, Francois H., Bardien, Soraya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219994/ https://www.ncbi.nlm.nih.gov/pubmed/34189277 http://dx.doi.org/10.1016/j.bbrep.2021.101035 |
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