CFTR-mediated anion secretion in parathyroid hormone-treated Caco-2 cells is associated with PKA and PI3K phosphorylation but not intracellular pH changes or Na(+)/K(+)-ATPase abundance

Parathyroid hormone (PTH) has previously been shown to enhance the transepithelial secretion of Cl(−) and HCO(3)(−) across the intestinal epithelia including Caco-2 monolayer, but the underlying cellular mechanisms are not completely understood. Herein, we identified the major signaling pathways tha...

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Detalles Bibliográficos
Autores principales: Chaimana, Rattana, Teerapornpuntakit, Jarinthorn, Jantarajit, Walailak, Lertsuwan, Kornkamon, Krungchanuchat, Saowalak, Panupinthu, Nattapon, Krishnamra, Nateetip, Charoenphandhu, Narattaphol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220001/
https://www.ncbi.nlm.nih.gov/pubmed/34189282
http://dx.doi.org/10.1016/j.bbrep.2021.101054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220001/
https://www.ncbi.nlm.nih.gov/pubmed/34189282
http://dx.doi.org/10.1016/j.bbrep.2021.101054

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