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A novel P38α MAPK activator Bruceine A exhibits potent anti-pancreatic cancer activity

Pancreatic cancer remains one of the cancers with the poorest prognosis bearing an overall 5-year survival rate of about 5%. Efficient new chemotherapic drugs are still highly desired. Here, bruceine A, a quassinoid identified from the dried fruits of Brucea javanica (L.) Merr., displayed the most p...

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Detalles Bibliográficos
Autores principales: Lu, Cai, Fan, Lu, Zhang, Peng-Fei, Tao, Wei-Wei, Yang, Cheng-Bin, Shang, Er-Xin, Chen, Fei-Yan, Che, Chun-Tao, Cheng, Hai-Bo, Duan, Jin-Ao, Zhao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220105/
https://www.ncbi.nlm.nih.gov/pubmed/34194669
http://dx.doi.org/10.1016/j.csbj.2021.06.011