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A novel P38α MAPK activator Bruceine A exhibits potent anti-pancreatic cancer activity
Pancreatic cancer remains one of the cancers with the poorest prognosis bearing an overall 5-year survival rate of about 5%. Efficient new chemotherapic drugs are still highly desired. Here, bruceine A, a quassinoid identified from the dried fruits of Brucea javanica (L.) Merr., displayed the most p...
Autores principales: | Lu, Cai, Fan, Lu, Zhang, Peng-Fei, Tao, Wei-Wei, Yang, Cheng-Bin, Shang, Er-Xin, Chen, Fei-Yan, Che, Chun-Tao, Cheng, Hai-Bo, Duan, Jin-Ao, Zhao, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220105/ https://www.ncbi.nlm.nih.gov/pubmed/34194669 http://dx.doi.org/10.1016/j.csbj.2021.06.011 |
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