Instrumental Heterogeneity in Sex-Specific Two-Sample Mendelian Randomization: Empirical Results From the Relationship Between Anthropometric Traits and Breast/Prostate Cancer

BACKGROUND: In two-sample Mendelian randomization (MR) studies, sex instrumental heterogeneity is an important problem needed to address carefully, which however is often overlooked and may lead to misleading causal inference. METHODS: We first employed cross-trait linkage disequilibrium score regre...

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Detalles Bibliográficos
Autores principales: Gao, Yixin, Zhang, Jinhui, Zhao, Huashuo, Guan, Fengjun, Zeng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220153/
https://www.ncbi.nlm.nih.gov/pubmed/34178025
http://dx.doi.org/10.3389/fgene.2021.651332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220153/
https://www.ncbi.nlm.nih.gov/pubmed/34178025
http://dx.doi.org/10.3389/fgene.2021.651332

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