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Spaceflight decelerates the epigenetic clock orchestrated with a global alteration in DNA methylome and transcriptome in the mouse retina

Astronauts exhibit an assortment of clinical abnormalities in their eyes during long-duration spaceflight. The purpose of this study was to determine whether spaceflight induces epigenomic and transcriptomic reprogramming in the retina or alters the epigenetic clock. The mice were flown for 37 days...

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Detalles Bibliográficos
Autores principales: Chen, Zhong, Stanbouly, Seta, Nishiyama, Nina C, Chen, Xin, Delp, Michael D, Qiu, Hongyu, Mao, Xiao W, Wang, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220224/
https://www.ncbi.nlm.nih.gov/pubmed/34179686
http://dx.doi.org/10.1093/pcmedi/pbab012