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Spaceflight decelerates the epigenetic clock orchestrated with a global alteration in DNA methylome and transcriptome in the mouse retina
Astronauts exhibit an assortment of clinical abnormalities in their eyes during long-duration spaceflight. The purpose of this study was to determine whether spaceflight induces epigenomic and transcriptomic reprogramming in the retina or alters the epigenetic clock. The mice were flown for 37 days...
Autores principales: | Chen, Zhong, Stanbouly, Seta, Nishiyama, Nina C, Chen, Xin, Delp, Michael D, Qiu, Hongyu, Mao, Xiao W, Wang, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220224/ https://www.ncbi.nlm.nih.gov/pubmed/34179686 http://dx.doi.org/10.1093/pcmedi/pbab012 |
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