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The redox-senescence axis and its therapeutic targeting

SIGNIFICANCE: Cellular growth arrest, associated with ‘senescence’, helps to safeguard against the accumulation of DNA damage which is often recognized as the underlying mechanism of a wide variety of age-related pathologies including cancer. Cellular senescence has also been described as a ‘double-...

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Detalles Bibliográficos
Autores principales: Ngoi, Natalie YL., Liew, Angeline QX., Chong, Stephen J.F., Davids, Matthew S., Clement, Marie-Veronique, Pervaiz, Shazib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220395/
https://www.ncbi.nlm.nih.gov/pubmed/34147844
http://dx.doi.org/10.1016/j.redox.2021.102032