Acute gene inactivation in the adult mouse liver using the CRISPR-Cas9 technology

Genetic manipulation in mice allows the discovery of gene function and biological mechanisms in vivo. The widely used Cre/LoxP system usually takes months to years especially when starting with the production of floxed alleles of a new gene of interest (GOI). Here, we describe a protocol using the C...

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Detalles Bibliográficos
Autores principales: Wang, Xiao, Xu, Bo-Lin, Chen, Xiao-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220398/
https://www.ncbi.nlm.nih.gov/pubmed/34189476
http://dx.doi.org/10.1016/j.xpro.2021.100611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220398/
https://www.ncbi.nlm.nih.gov/pubmed/34189476
http://dx.doi.org/10.1016/j.xpro.2021.100611

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