Universal capability of 3-ketosteroid Δ(1)-dehydrogenases to catalyze Δ(1)-dehydrogenation of C17-substituted steroids

BACKGROUND: 3-Ketosteroid Δ(1)-dehydrogenases (KSTDs) are the enzymes involved in microbial cholesterol degradation and modification of steroids. They catalyze dehydrogenation between C1 and C2 atoms in ring A of the polycyclic structure of 3-ketosteroids. KSTDs substrate spectrum is broad, even tho...

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Detalles Bibliográficos
Autores principales: Wójcik, Patrycja, Glanowski, Michał, Wojtkiewicz, Agnieszka M., Rohman, Ali, Szaleniec, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220720/
https://www.ncbi.nlm.nih.gov/pubmed/34162386
http://dx.doi.org/10.1186/s12934-021-01611-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220720/
https://www.ncbi.nlm.nih.gov/pubmed/34162386
http://dx.doi.org/10.1186/s12934-021-01611-5

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