Role of the intestinal microbiome and microbial-derived metabolites in immune checkpoint blockade immunotherapy of cancer

Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block immune inhibitory pathways. Administration of ICIs augments T cell-mediated immune responses against tumor, resulting in improved overall survival in cancer patients. It has emerged that the intestinal microbiome can modulate r...

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Detalles Bibliográficos
Autores principales: Hayase, Eiko, Jenq, Robert R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220726/
https://www.ncbi.nlm.nih.gov/pubmed/34162429
http://dx.doi.org/10.1186/s13073-021-00923-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220726/
https://www.ncbi.nlm.nih.gov/pubmed/34162429
http://dx.doi.org/10.1186/s13073-021-00923-w

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