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Methyltransferase-directed orthogonal tagging and sequencing of miRNAs and bacterial small RNAs
BACKGROUND: Targeted installation of designer chemical moieties on biopolymers provides an orthogonal means for their visualisation, manipulation and sequence analysis. Although high-throughput RNA sequencing is a widely used method for transcriptome analysis, certain steps, such as 3′ adapter ligat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220740/ https://www.ncbi.nlm.nih.gov/pubmed/34158037 http://dx.doi.org/10.1186/s12915-021-01053-w |